Naproxen sodium, sold under brand names such as Aleve, is available by prescription or over the counter. Aleve is the most common brand name available without a prescription. It is most commonly used for pain management. Aleve is for short-term pain relief, while a prescription for naproxen sodium is for pain that is more serious and longer treatment.
Most Common
Common side effects of naproxen sodium are drowsiness, tiredness, dizziness, headache, diarrhea, heartburn, constipation, and upset stomach.
Unlikely
Stomach pain, swelling of the hands or feet, difficulty swallowing, fainting, irregular heartbeat, sudden weight gain, sudden mood changes, and severe headache are unlikely, but serious side effects.
Sensory
Naproxen sodium may cause some vision or hearing changes. These side effects are unlikely but very serious.
Rare
Naproxen sodium may cause serious bleeding in the stomach or intestines. These side effects are rarely fatal but are very serious.
Serious
Other serious side effects include chest pain, shortness of breath, slurred speech, persistent stomach pain, black stools, coffee grounds-like vomit, and weakness on one side of the body.
Blood Clots
The drug may cause blood clots that could result in a heart attack or stroke. These two things are very serious but very rare when taking naproxen sodium.
Liver Disease
Rarely, the drug has been known to cause possibly fatal liver disease. Signs of liver disease include dark urine, extreme tiredness, persistent nausea or vomiting, severe abdominal pain, and yellowing of the eyes or skin.
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